Switching from one medication to another may be associated with withdrawal and rebound symptoms.

Switching antidepressants and/or antipsychotics requires careful guidance in order to avoid potential problems.

Discuss the best switch strategy with your physician.

When prescribing medication, I often use the mnemonic "OSCAR" as a guide to sensible prescribing. The mnemonic highlights the 5 steps towards rational pharmacotherapy. These steps are:

O  Optimize: Diagnosis, Dose, Duration of trial, Adherence

S  Switch: To another agent if the initial medication fails

C  Combine: Use 2 antidepressants at same time

A  Augment: Add agent to "boost" effect of initially prescribed antidepressant

R  Review all the steps taken so far to ensure prescribing was rational